SCHEMBL20173255

SCHEMBL20173255

Cc1c(F)cc(-c2ccc(C3OCC(C)CO3)cc2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.35
CYP11B2 P19099 4/20 0.35
FFAR4 Q5NUL3 2/20 0.32
RAB9A P51151 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615257 0.90 CYP11B1 (0.34) CYP11B1CYP11B2
SCHEMBL9763685 0.89 CYP11B1 (0.36) CYP11B1CYP11B2FFAR4MEN1KMT2A
SCHEMBL19844682 0.84 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL10013945 0.84 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL17192663 0.84 CYP11B1 (0.33) CYP11B1CYP11B2RAB9A
SCHEMBL13171680 0.84 CYP11B1 (0.33) CYP11B1CYP11B2
SCHEMBL13408477 0.83
SCHEMBL19687728 0.82 CYP11B1 (0.34) CYP11B1CYP11B2
SCHEMBL16790917 0.82 MEN1 (0.39) MEN1KMT2A
SCHEMBL19678410 0.81 PDE3B (0.41) CYP11B1CYP11B2FFAR4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180142154-A1 LIQUID CRYSTAL COMPOSITION HAVING GOOD PHOTOSTABILITY AND THERMOSTABILITY, AND LIQUID CRYSTAL DISPLAY ELEMENT JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-05-24 US disclosed