SCHEMBL20174148

SCHEMBL20174148

C=CC(=O)Oc1ccc(C(=O)Oc2ccc3cc(OC(=O)C(=C)C)ccc3c2)cc1OC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.43
KMT2A Q03164 11/20 0.42
MEN1 O00255 5/20 0.42
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
HGFAC Q04756 1/20 0.39
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
ESR1 P03372 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
MAPK1 P28482 2/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16978322 0.90 ELANE (0.39) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL16978324 0.90 ELANE (0.39) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL816216 0.87 ELANE (0.40) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL11961761 0.86 POLB (0.42) ELANEKMT2AMEN1TDP1TSHR
SCHEMBL11961821 0.86 ELANE (0.56) ELANEKMT2AMEN1MAPTTDP1
SCHEMBL15338838 0.86 KMT2A (0.49) ELANEKMT2AMEN1MAPTKDM4E
SCHEMBL15338839 0.86 KMT2A (0.46) KMT2AMEN1MAPTTDP1HGFAC
SCHEMBL15339145 0.84 ELANE (0.42) ELANEKMT2AMAPTTDP1KDM4E
SCHEMBL15339139 0.84 KMT2A (0.51) ELANEKMT2AMEN1MAPTKDM4E
SCHEMBL12604131 0.84 KMT2A (0.47) KMT2AMEN1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed