Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14379282 | 0.82 | MEN1 (0.51) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10184550 | 0.82 | MAPT (0.65) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15693777 | 0.81 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14402949 | 0.81 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18267329 | 0.81 | MEN1 (0.47) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14583726 | 0.76 | MEN1 (0.46) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13760317 | 0.76 | MEN1 (0.46) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18335256 | 0.76 | MAPT (0.54) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18335257 | 0.76 | MAPT (0.54) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10119039 | 0.75 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091446-A1 | PROCESS FOR DYEING AND FOAMING THERMOPLASTIC POLYURETHANE | HUNTSMAN INTERNATIONAL LLC (US) | 2018-05-24 | — | — | WO | disclosed |