Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165825 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL20168869 | 0.76 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL22837285 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20176893 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20165473 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL20165494 | 0.69 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20165491 | 0.69 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20165891 | 0.68 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL22817819 | 0.68 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL20165882 | 0.68 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541784-B1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RES LABORATORIES SWEDEN AB (SE) | 2023-09-13 | — | — | EP | disclosed |
| WO-2018091687-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2018-05-24 | — | — | WO | disclosed |