Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | OXTR | P30559 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165880 | 0.86 | SLC6A4 (0.41) | SLC6A4HTR6HTR2CHTR2BACACB | |
| SCHEMBL20176661 | 0.83 | SLC6A4 (0.44) | SLC6A4ACACBOXTRSCN1ASCN8A | |
| SCHEMBL20166170 | 0.78 | SLC6A4 (0.46) | SLC6A4HTR6HTR2CHTR2BOXTR | |
| SCHEMBL20165874 | 0.76 | SLC6A4 (0.44) | SLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL20176664 | 0.72 | SLC6A4 (0.35) | SLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL11288497 | 0.71 | SLC6A2 (0.50) | SLC6A4 | |
| SCHEMBL20165881 | 0.71 | SLC6A4 (0.60) | SLC6A4HTR6HTR2CHTR2BSCN1A | |
| SCHEMBL20068828 | 0.71 | SLC6A4 (0.52) | SLC6A4HTR6HTR2CHTR2B | |
| SCHEMBL10261794 | 0.70 | SLC6A2 (0.47) | SLC6A4HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL20168801 | 0.70 | SLC6A4 (0.34) | SLC6A4HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091687-A1 | NOVEL AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB (SE) | 2018-05-24 | — | — | WO | disclosed |