Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112205 | 0.83 | PHGDH (0.52) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL30871888 | 0.77 | SMN1; SMN2 (0.40) | PHGDHSMN1; SMN2ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL3723780 | 0.76 | PHGDH (0.61) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL28364765 | 0.75 | SMN1; SMN2 (0.49) | PHGDHSMN1; SMN2ALDH1A1HSD17B10MAPT | |
| SCHEMBL21753955 | 0.74 | PHGDH (0.59) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL7784610 | 0.74 | PHGDH (0.59) | PHGDHALDH1A1HSD17B10TAS2R38CYP3A4 | |
| SCHEMBL28501426 | 0.74 | PHGDH (0.59) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL3075966 | 0.74 | PHGDH (0.77) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL2702341 | 0.73 | PHGDH (0.57) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 | |
| SCHEMBL27267591 | 0.73 | PHGDH (0.57) | PHGDHSMN1; SMN2ALDH1A1HSD17B10TAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167982-B | Block copolymer and method for producing block copolymer | 电化株式会社 | 2022-10-04 | — | — | CN | disclosed |
| US-20180141912-A1 | VERSATILE RAFT AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141912-A1 | VERSATILE RAFT AGENT | CNKSR1, CNR2, CNR1 | PHGDH 4855/4885SMN1; SMN2 1810/4885ALDH1A1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.