Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190879 | 0.81 | — | — | |
| SCHEMBL15310039 | 0.77 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL268147 | 0.75 | — | — | |
| SCHEMBL8818203 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL268075 | 0.75 | — | — | |
| SCHEMBL19729650 | 0.75 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL13186335 | 0.75 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL14216330 | 0.75 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL14586670 | 0.73 | TSHR (0.39) | TSHR | |
| SCHEMBL19248348 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093696-A1 | INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |