⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17823320 | 0.91 | — | — | |
| SCHEMBL20178687 | 0.90 | — | — | |
| SCHEMBL17823288 | 0.89 | — | — | |
| SCHEMBL17823242 | 0.89 | — | — | |
| SCHEMBL17823255 | 0.89 | — | — | |
| SCHEMBL17823259 | 0.88 | — | — | |
| SCHEMBL17823260 | 0.88 | — | — | |
| SCHEMBL19665160 | 0.87 | — | — | |
| SCHEMBL17823290 | 0.86 | — | — | |
| SCHEMBL17823318 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981976-B2 | Piperidine substituted pyrazolo[1,5-A]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV) | JANSSEN SCIENCES IRELAND UC (IE) | 2018-05-29 | — | — | US | claimed |