Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.84 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20178926 | 0.92 | MAP3K5 (1.00) | MAP3K5MAP3K6 | |
| SCHEMBL29949481 | 0.92 | MAP3K5 (1.00) | MAP3K5MAP3K6 | |
| SCHEMBL28848722 | 0.87 | MAP3K5 (0.82) | MAP3K5MAP3K6 | |
| SCHEMBL29949189 | 0.87 | MAP3K5 (0.82) | MAP3K5MAP3K6 | |
| SCHEMBL20178923 | 0.87 | MAP3K5 (0.82) | MAP3K5MAP3K6 | |
| SCHEMBL20178916 | 0.84 | MAP3K5 (0.71) | MAP3K5AKT1 | |
| SCHEMBL20178922 | 0.84 | MAP3K5 (0.77) | MAP3K5AKT1 | |
| SCHEMBL233559 | 0.83 | MAP3K5 (0.74) | MAP3K5AKT1 | |
| SCHEMBL233558 | 0.83 | MAP3K5 (0.74) | MAP3K5AKT1 | |
| SCHEMBL20178934 | 0.82 | MAP3K5 (0.82) | MAP3K5MAP3K6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090869-A1 | AMIDE DERIVATIVE AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2018-05-24 | — | — | WO | disclosed |