Pyridine

Pyridine

SCHEMBL2017900

CN(C)C=O.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.32
KMT2A Q03164 1/20 0.32
CHRM5 P08912 1/20 0.31
CHKA P35790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL11554309 1.00 TSHR (0.50) TSHRNAPRTTDP1HTTKDM4E
Pyridine SCHEMBL27296235 0.97 TSHR (0.47) TSHRNAPRTTDP1HTTKDM4E
Pyridine SCHEMBL28099571 0.97 TSHR (0.47) TSHRNAPRTTDP1HTTKDM4E
Pyridine SCHEMBL2727868 0.89 TSHR (0.39) TSHRNAPRTTDP1
Pyridine SCHEMBL11552252 0.89 TSHR (0.39) TSHRNAPRTTDP1
Pyridine SCHEMBL10004135 0.87 TSHR (0.38) TSHRNAPRTTDP1
Pyridine SCHEMBL186397 0.83 TSHR (0.39) TSHRNAPRTTDP1HTTKDM4E
Benzene SCHEMBL537377 0.82 TSHR (0.75) TSHRHTTKMT2A
Pyridine SCHEMBL5969174 0.79
Pyridine SCHEMBL9366683 0.78 TSHR (0.69) TSHRNAPRTTDP1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724779-A Amidoalkane disulfide compound, preparation method and application thereof 四川大学 2023-03-03 CN claimed
CN-115417813-A Preparation method of smoke sulfamide 淄博新农基作物科学有限公司 2022-12-02 CN claimed
CN-113956270-A Preparation method of main degradation product of ceforanide 成都大学 2022-01-21 CN claimed
CN-113185447-A Phthaloyl cysteamine compound, preparation method and use thereof 四川大学 2021-07-30 CN claimed
CN-109265362-B 2, 5-dihydroxy terephthalamide compounds, preparation method and application thereof 四川大学 2021-04-27 CN claimed
CN-111170884-A Salicylamide compounds, preparation method and application thereof 四川大学 2020-05-19 CN claimed
CN-103113593-B Preparation method of hydroxylated multi-wall carbon nanotube-polysilane composite material UNIV HARBIN SCIENCE & TECH 2014-08-27 CN claimed
CN-103113593-A Preparation method of hydroxylated multi-wall carbon nanotube-polysilane composite material UNIV HARBIN SCIENCE & TECH 2013-05-22 CN claimed
EP-1708991-B1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LTD (GB) 2007-10-17 EP claimed
EP-1708992-B1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LTD (GB) 2007-08-08 EP claimed
EP-1708992-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES Pfizer Limited (GB) 2006-10-11 EP claimed
EP-1708991-A2 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES Pfizer Limited (GB) 2006-10-11 EP claimed
WO-2005080313-A9 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LTD (GB) 2006-08-31 WO claimed
WO-2005080324-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LIMITED (GB) 2005-09-01 WO claimed
WO-2005080313-A2 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LIMITED (GB) 2005-09-01 WO claimed
EP-0915874-B1 PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES IND CHIMICA SRL (IT) 2003-12-10 EP claimed
EP-0915874-A2 PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES INDUSTRIALE CHIMICA S.r.l. (IT) 1999-05-19 EP claimed
WO-1998003553-A1 PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES INDUSTRIALE CHIMICA S.R.L. (IT) 1998-01-29 WO claimed
CN-118239953-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2024-06-25 CN disclosed
US-3951982-A Trialkylsilyl esters of 6(substituted amino)phenyl-1,-dihydro-2-oxonicotinic acid, methods for their production and conversion to the corresponding acid chlorides PARKE, DAVIS & COMPANY 1976-04-20 US disclosed