Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26038924 | 0.85 | FOLH1 (0.42) | FOLH1ANPEPENPEPMRGPRX4TP53 | |
| SCHEMBL26039018 | 0.85 | FOLH1 (0.40) | FOLH1ANPEPENPEPCTSBMRGPRX4 | |
| SCHEMBL21577909 | 0.84 | FOLH1 (0.46) | FOLH1ANPEPENPEPMRGPRX4TP53 | |
| SCHEMBL20179207 | 0.83 | FOLH1 (0.54) | FOLH1 | |
| SCHEMBL20179208 | 0.81 | FOLH1 (0.43) | FOLH1ANPEPENPEPMRGPRX4TP53 | |
| SCHEMBL20168737 | 0.79 | FOLH1 (0.51) | FOLH1ANPEPENPEPSLC7A5 | |
| SCHEMBL21578003 | 0.72 | FOLH1 (0.48) | FOLH1ANPEPENPEPMRGPRX4SLC7A5 | |
| SCHEMBL21577916 | 0.72 | SLC7A5 (0.52) | FOLH1SLC7A5 | |
| SCHEMBL20179153 | 0.71 | SLC7A5 (0.51) | FOLH1SLC7A5 | |
| SCHEMBL21577919 | 0.71 | FOLH1 (0.45) | FOLH1ANPEPENPEPMRGPRX4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |