Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179169 | 0.89 | FOLH1 (0.43) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL20179164 | 0.89 | ANPEP (0.43) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL26038893 | 0.89 | FOLH1 (0.44) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL26038895 | 0.85 | FOLH1 (0.45) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL21577908 | 0.85 | FOLH1 (0.44) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL20179193 | 0.85 | FOLH1 (0.56) | ANPEPENPEPFOLH1 | |
| SCHEMBL26038897 | 0.84 | FOLH1 (0.44) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL20179209 | 0.83 | FOLH1 (0.42) | ANPEPENPEPFOLH1MEP1BSLC7A5 | |
| SCHEMBL20179208 | 0.83 | FOLH1 (0.43) | ANPEPENPEPFOLH1SLC7A5 | |
| SCHEMBL20168307 | 0.79 | FOLH1 (0.51) | ANPEPENPEPFOLH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094334-A1 | PRODRUGS OF HYDROXAMATE-BASED GCPII INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-24 | — | — | WO | disclosed |