⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19481581 | 0.83 | — | — | |
| SCHEMBL18541568 | 0.80 | — | — | |
| SCHEMBL22751605 | 0.78 | TDP1 (0.34) | — | |
| SCHEMBL16710882 | 0.78 | — | — | |
| SCHEMBL25848509 | 0.76 | — | — | |
| SCHEMBL16020370 | 0.76 | — | — | |
| SCHEMBL18649898 | 0.76 | — | — | |
| SCHEMBL19728613 | 0.74 | ODC1 (0.30) | — | |
| SCHEMBL22751614 | 0.74 | GAA (0.37) | — | |
| SCHEMBL20048275 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2018-05-24 | — | — | US | disclosed |