Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883787 | 0.78 | TSHR (0.61) | TSHRSMN1; SMN2 | |
| SCHEMBL5133414 | 0.78 | ABCC4 (0.48) | TSHR | |
| SCHEMBL2357535 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2 | |
| SCHEMBL229944 | 0.77 | — | — | |
| SCHEMBL28667395 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL9794525 | 0.77 | — | — | |
| SCHEMBL25135488 | 0.75 | — | — | |
| SCHEMBL9516420 | 0.75 | TSHR (0.52) | TSHRSMN1; SMN2 | |
| SCHEMBL28894331 | 0.74 | SMN1; SMN2 (0.42) | TSHRSMN1; SMN2 | |
| SCHEMBL11879219 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254786-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| EP-2209496-B1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | UNIV VANDERBILT (US) | 2019-05-08 | — | — | EP | disclosed |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254786-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | DSTN, PARN, CTSA | TSHR 2807/4885SMN1; SMN2 2480/4885 |
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | DSTN, PARN, CTSA | TSHR 2807/4885SMN1; SMN2 2480/4885 |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | DSTN, PARN, CTSA | TSHR 2807/4885SMN1; SMN2 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.