Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21579806 | 0.88 | F12 (0.73) | F12 | |
| SCHEMBL20166269 | 0.82 | F12 (0.65) | F12 | |
| SCHEMBL21579822 | 0.78 | F12 (0.79) | F12 | |
| SCHEMBL26021631 | 0.78 | F12 (0.79) | F12 | |
| SCHEMBL21579633 | 0.77 | F12 (0.65) | F12 | |
| SCHEMBL21571301 | 0.77 | F12 (1.00) | F12 | |
| SCHEMBL30633191 | 0.77 | F12 (1.00) | F12 | |
| SCHEMBL30633203 | 0.76 | F12 (1.00) | F12 | |
| SCHEMBL21579579 | 0.76 | F12 (1.00) | F12 | |
| SCHEMBL26016585 | 0.75 | F12 (0.56) | F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |