Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664232 | 0.90 | ESR1 (0.75) | ESR1 | |
| SCHEMBL19273589 | 0.85 | ESR1 (0.81) | ESR1 | |
| SCHEMBL19132594 | 0.85 | ESR1 (0.81) | ESR1 | |
| SCHEMBL20165080 | 0.84 | ESR1 (0.80) | ESR1 | |
| SCHEMBL20165083 | 0.84 | ESR1 (0.80) | ESR1 | |
| SCHEMBL20179801 | 0.84 | ESR1 (0.61) | ESR1 | |
| Bromide SCHEMBL29756696 | 0.83 | ESR1 (0.60) | ESR1 | |
| Bromide SCHEMBL20165378 | 0.83 | ESR1 (0.60) | ESR1 | |
| Bromide SCHEMBL20165380 | 0.83 | ESR1 (0.60) | ESR1 | |
| SCHEMBL29243198 | 0.82 | ESR1 (0.64) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |