Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 11/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273758 | 0.87 | ELANE (0.44) | MEN1KMT2AELANECA2ESR1 | |
| SCHEMBL20165175 | 0.86 | ELANE (0.36) | MEN1KMT2AELANECA2ESR1 | |
| SCHEMBL26187674 | 0.85 | ELANE (0.37) | MEN1KMT2AELANECA2 | |
| SCHEMBL30613266 | 0.85 | ELANE (0.37) | MEN1KMT2AELANECA2 | |
| SCHEMBL26187600 | 0.85 | ELANE (0.37) | MEN1KMT2AELANECA2ESR1 | |
| SCHEMBL20687054 | 0.84 | ESR1 (0.38) | ESR1ESR2 | |
| SCHEMBL19273720 | 0.80 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL19273587 | 0.78 | ELANE (0.44) | MEN1KMT2AELANECA2 | |
| SCHEMBL30624506 | 0.77 | CHEK2 (0.36) | MEN1KMT2A | |
| SCHEMBL26187309 | 0.77 | CHEK2 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |