Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756718 | 1.00 | ESR1 (0.62) | ESR1 | |
| SCHEMBL20165195 | 1.00 | ESR1 (0.62) | ESR1 | |
| SCHEMBL29756725 | 0.94 | ESR1 (0.59) | ESR1 | |
| SCHEMBL20165037 | 0.94 | ESR1 (0.59) | ESR1 | |
| SCHEMBL31739213 | 0.89 | ESR1 (0.78) | ESR1 | |
| SCHEMBL19132405 | 0.89 | ESR1 (0.78) | ESR1 | |
| SCHEMBL21253419 | 0.89 | ESR1 (0.78) | ESR1 | |
| SCHEMBL29756791 | 0.87 | ESR1 (0.78) | ESR1 | |
| SCHEMBL20165101 | 0.87 | ESR1 (0.78) | ESR1 | |
| SCHEMBL20165276 | 0.87 | ESR1 (0.77) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |