Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020279 | 0.91 | CYSLTR2 (0.39) | TSHRCYSLTR2CYSLTR1 | |
| SCHEMBL2024316 | 0.90 | CYSLTR2 (0.44) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL1841247 | 0.89 | TSHR (0.43) | TSHRADRA2AADRA2BADRA2CGABRA1 | |
| SCHEMBL2023168 | 0.89 | CYSLTR2 (0.46) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL2021339 | 0.89 | CYSLTR2 (0.46) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL2023177 | 0.89 | CYSLTR2 (0.46) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL2018806 | 0.89 | CYSLTR2 (0.46) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL2025311 | 0.89 | CYSLTR2 (0.46) | TSHRCYSLTR2CYSLTR1ALOX5HTT | |
| SCHEMBL2019657 | 0.88 | TSHR (0.41) | TSHRGABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL2022483 | 0.87 | TSHR (0.33) | TSHRGABRA1GABRB2HTR1APRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160476-A1 | N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester | ALKBH3, CPS1, APEH | TSHR 2998/4885ADRA2A 3245/4885ADRA2B 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.