Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 9/20 | 0.75 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21542318 | 1.00 | GRM7 (0.75) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL20165981 | 1.00 | GRM7 (0.75) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL21542320 | 1.00 | GRM7 (0.75) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL20165982 | 1.00 | GRM7 (0.75) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL20165979 | 1.00 | GRM7 (0.75) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL21542214 | 0.90 | GRM7 (0.76) | GRM7LTB4RLTB4R2P2RX7 | |
| SCHEMBL21542216 | 0.90 | GRM7 (0.76) | GRM7LTB4RLTB4R2P2RX7 | |
| SCHEMBL20182770 | 0.90 | GRM7 (0.76) | GRM7LTB4RLTB4R2P2RX7 | |
| SCHEMBL21542206 | 0.86 | GRM7 (0.61) | GRM7LTB4RLTB4R2P2RX7TRPM8 | |
| SCHEMBL21542241 | 0.86 | GRM7 (0.61) | GRM7LTB4RLTB4R2P2RX7TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541812-B1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICALS CO (JP) | 2023-06-14 | — | — | EP | disclosed |
| WO-2018092921-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-24 | — | — | WO | disclosed |