Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 9/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21559932 | 0.92 | GRM7 (0.63) | GRM7P2RX7DGAT2 | |
| SCHEMBL29909634 | 0.92 | GRM7 (0.63) | GRM7P2RX7DGAT2 | |
| SCHEMBL21542298 | 0.86 | GRM7 (0.71) | GRM7P2RX7DGAT2MEN1KMT2A | |
| SCHEMBL21542296 | 0.86 | GRM7 (0.71) | GRM7P2RX7DGAT2MEN1KMT2A | |
| SCHEMBL20182784 | 0.86 | GRM7 (0.71) | GRM7P2RX7DGAT2MEN1KMT2A | |
| SCHEMBL21542216 | 0.81 | GRM7 (0.76) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL20182770 | 0.81 | GRM7 (0.76) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL21542214 | 0.81 | GRM7 (0.76) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL21542337 | 0.78 | GRM7 (0.71) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL20182935 | 0.78 | GRM7 (0.71) | GRM7P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541812-B1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICALS CO (JP) | 2023-06-14 | — | — | EP | disclosed |
| WO-2018092921-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-24 | — | — | WO | disclosed |