Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182987 | 0.89 | GRM7 (0.51) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL21542219 | 0.89 | GRM7 (0.51) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL21542221 | 0.89 | GRM7 (0.51) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL20165963 | 0.84 | GRM7 (0.46) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL20165965 | 0.84 | GRM7 (0.46) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL20165964 | 0.84 | GRM7 (0.46) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL19960687 | 0.83 | GRM7 (0.55) | GRM7TSHRALDH1A1LMNAGAA | |
| SCHEMBL21542235 | 0.80 | GRM7 (0.55) | GRM7TSHRLMNAGAANPSR1 | |
| SCHEMBL21542236 | 0.80 | GRM7 (0.55) | GRM7TSHRLMNAGAANPSR1 | |
| SCHEMBL20182937 | 0.80 | GRM7 (0.55) | GRM7TSHRLMNAGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092921-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-24 | — | — | WO | disclosed |