Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635577 | 0.77 | AAK1 (1.00) | AAK1 | |
| SCHEMBL20184205 | 0.69 | AAK1 (0.79) | AAK1 | |
| SCHEMBL20184200 | 0.68 | AAK1 (0.62) | AAK1 | |
| SCHEMBL16635622 | 0.67 | AAK1 (0.49) | AAK1 | |
| SCHEMBL16636243 | 0.66 | AAK1 (1.00) | AAK1 | |
| SCHEMBL18033858 | 0.66 | AAK1 (0.57) | AAK1 | |
| SCHEMBL20184203 | 0.65 | AAK1 (0.60) | AAK1 | |
| SCHEMBL16646845 | 0.65 | AAK1 (1.00) | AAK1 | |
| SCHEMBL401804 | 0.64 | NPC1 (0.52) | AAK1 | |
| SCHEMBL16636675 | 0.63 | AAK1 (1.00) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054955-B1 | PYRROLOTRIAZINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-30 | — | — | EP | disclosed |