Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438723 | 1.00 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL17925120 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL16438733 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL17925088 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL16438931 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL17925108 | 0.94 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL16438746 | 0.94 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL14919331 | 0.93 | KCNJ1 (0.86) | KCNJ1KCNH2 | |
| SCHEMBL14919329 | 0.93 | KCNJ1 (0.86) | KCNJ1KCNH2 | |
| SCHEMBL16438944 | 0.90 | KCNJ1 (1.00) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027625-B1 | SPIRO-FUSED DERIVATIVES OF PIPERIDINE USEFUL FOR THE TREATMENT OF INTER ALIA HYPERTENSION AND ACUTE OR CHRONIC HEART FAILURE | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | disclosed |