Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184605 | 0.91 | JAK3 (0.59) | JAK3JAK1 | |
| SCHEMBL20184560 | 0.87 | JAK3 (0.61) | JAK3JAK1 | |
| SCHEMBL20184404 | 0.87 | JAK3 (0.59) | JAK3JAK1 | |
| SCHEMBL20184684 | 0.87 | JAK3 (0.60) | JAK3JAK1 | |
| SCHEMBL20184330 | 0.86 | JAK3 (0.59) | JAK3JAK1 | |
| SCHEMBL20184524 | 0.86 | JAK3 (0.59) | JAK3JAK1 | |
| SCHEMBL20184505 | 0.85 | JAK3 (0.80) | JAK3JAK1 | |
| SCHEMBL20184490 | 0.84 | JAK3 (0.61) | JAK3JAK1 | |
| SCHEMBL20184333 | 0.84 | JAK3 (0.61) | JAK3JAK1 | |
| SCHEMBL20184514 | 0.83 | JAK3 (0.61) | JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788000-B1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | claimed |
| EP-2788000-B1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | disclosed |