Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808281 | 1.00 | TDP1 (0.48) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL20184981 | 1.00 | TDP1 (0.48) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL991815 | 0.93 | TDP1 (0.54) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL18256747 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL18256745 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL18866874 | 0.87 | TDP1 (0.49) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL5490993 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL18257733 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL18257737 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 | |
| SCHEMBL20185050 | 0.87 | TDP1 (0.65) | TDP1MAOAMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10111437-B2 | Substituted guanidines as fungicides | NIPPON SODA CO., LTD. (JP) | 2018-10-30 | — | — | US | disclosed |
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | GUCY1A2, GUCY1B2, GUCY1A1 | TDP1 453/4885MAOA 792/4885MAOB 826/4885 |
| US-10111437-B2 | Substituted guanidines as fungicides | GUCY1A2, GUCY1B2, GUCY1A1 | TDP1 500/4885MAOA 438/4885MAOB 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.