Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123195 | 1.00 | IDH1 (0.51) | IDH1LCK | |
| SCHEMBL20209684 | 0.88 | IDH1 (0.50) | IDH1LCK | |
| SCHEMBL20209255 | 0.88 | IDH1 (0.50) | IDH1LCK | |
| SCHEMBL20209259 | 0.87 | IDH1 (0.46) | IDH1LCK | |
| SCHEMBL30122997 | 0.87 | IDH1 (0.46) | IDH1LCK | |
| SCHEMBL20196458 | 0.87 | IDH1 (0.46) | IDH1LCK | |
| SCHEMBL20209434 | 0.85 | IDH1 (0.52) | IDH1LCK | |
| SCHEMBL20209174 | 0.85 | IDH1 (0.52) | IDH1LCK | |
| SCHEMBL30122768 | 0.84 | IDH1 (0.52) | IDH1LCK | |
| SCHEMBL30123272 | 0.84 | IDH1 (0.52) | IDH1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018095344-A1 | ISOCITRATE DEHYDROGENASE (IDH) INHIBITOR | SHANGHAI METON PHARMACEUTICAL CO., LTD (CN) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018095344-A1 | ISOCITRATE DEHYDROGENASE (IDH) INHIBITOR | SHANGHAI METON PHARMACEUTICAL CO., LTD (CN) | 2018-05-31 | — | — | WO | disclosed |