Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357845 | 0.90 | MAPT (0.36) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL20610202 | 0.89 | MAPT (0.35) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL23302278 | 0.80 | MAPT (0.35) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL23302393 | 0.80 | PDE10A (0.36) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL20610216 | 0.76 | KDM4E (0.41) | MAPTKDM4EHTTSMN1; SMN2POLB | |
| SCHEMBL20209413 | 0.75 | MAPT (0.36) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL23302327 | 0.75 | MAPT (0.33) | MAPTKDM4EPOLBCOMT | |
| SCHEMBL24212637 | 0.75 | KDM4E (0.38) | MAPTKDM4EHTTHSP90AA1SMN1; SMN2 | |
| SCHEMBL20610182 | 0.74 | KDM4E (0.31) | MAPTKDM4E | |
| SCHEMBL20385117 | 0.72 | SMN1; SMN2 (0.42) | MAPTKDM4EHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018095795-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018095795-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-31 | — | — | WO | disclosed |