SCHEMBL2019008

SCHEMBL2019008

C=C[K].FB(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452261 0.78
Ammonia Solution, Strong SCHEMBL28236722 0.72
SCHEMBL28120290 0.72
SCHEMBL15106937 0.70
SCHEMBL2019007 0.70
Propene SCHEMBL28202545 0.70
SCHEMBL21840094 0.70
Boric Acid SCHEMBL21616734 0.70
SCHEMBL14250511 0.67
Ethylene SCHEMBL2132449 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118930553-A 5,6,7, 8-Tetrahydrofuran [3,4-g ] isoquinoline-3 (1H) -ketone compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-11-12 CN claimed
CN-118930552-A Isobenzofuran-1 (3H) -one compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-11-12 CN claimed
CN-114249885-B Bimetallic catalyst and preparation method and application thereof 万华化学集团股份有限公司 2023-05-26 CN claimed
CN-112225883-B Four kinds of D-A' - (pi-A) 2 Metal complex of polymeric pyridine derivative and preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-113321670-B Four kinds of D-A' - (pi-A) 2 Polymeric alkylated pyridine derivative metal complex and preparation method and application thereof 湘潭大学 2023-05-26 CN claimed
CN-112592280-B Preparation method of racemic salbutamol 青岛职业技术学院 2023-05-23 CN claimed
CN-113735999-B Porous polymer with high stability and flexibility and application thereof 浙江理工大学龙港研究院有限公司 2023-02-21 CN claimed
CN-114196035-B Four polymerization complexes using phenanthroline derivative as ligand, preparation method and application thereof 湘潭大学 2022-12-09 CN claimed
CN-114380682-A Synthesis method of 2, 3-difluoro-4-methoxyphenylacetic acid 上海毕得医药科技股份有限公司 2022-04-22 CN claimed
CN-114196035-A Four polymerization complexes using phenanthroline derivative as ligand, preparation method and application thereof 湘潭大学 2022-03-18 CN claimed
CN-113735999-A Porous polymer with high stability and flexibility and application thereof 浙江理工大学龙港研究院有限公司 2021-12-03 CN claimed
CN-108912708-B Anti-stripping composite modified asphalt and preparation method thereof 广东省城乡规划设计研究院 2020-11-20 CN claimed
CN-107892680-B Antituberculous compound and synthesis method and application thereof 北京大学 2020-11-10 CN claimed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-20250388583-A1 COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION ENGINE BIOSCIENCES PTE LTD (SG) 2025-12-25 US disclosed
US-20250282781-A1 APOL1 INHIBITORS AND METHODS OF USE HERCULES CAPITAL, INC., AS AGENT 2025-09-11 US disclosed
US-20120264761-A1 Aminobenzoquinazolinone M1 Receptor Positive Allosteric Modulators MERCK SHARP & DOHME LLC 2012-10-18 US disclosed
US-20110245205-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME LLC 2011-10-06 US disclosed
WO-2011084371-A1 AMINOBENZOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS MERCK SHARP & DOHME CORP. (US) 2011-07-14 WO disclosed
WO-2011075515-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2011-06-23 WO disclosed