Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.62 |
| ▸ | GSK3A | P49840 | 13/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ATR | Q13535 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205158 | 0.92 | GSK3B (0.71) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20205058 | 0.89 | GSK3B (0.69) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20205202 | 0.89 | GSK3B (0.69) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20204938 | 0.88 | GSK3B (0.64) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20205198 | 0.88 | GSK3B (0.68) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20204987 | 0.86 | GSK3B (0.64) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20189758 | 0.86 | GSK3B (0.66) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20190762 | 0.83 | GSK3B (0.64) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20204995 | 0.82 | GSK3B (0.70) | GSK3BGSK3AMAPTATR | |
| SCHEMBL20190395 | 0.82 | GSK3B (0.62) | GSK3BGSK3AMAPTATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544613-A1 | GSK-3 INHIBITORS | Bristol-Myers Squibb Company (US) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018098412-A1 | GSK-3 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-31 | — | — | WO | disclosed |