Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490563 | 1.00 | KMT2A (0.59) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL5579212 | 0.93 | KMT2A (0.55) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL20193277 | 0.87 | KMT2A (0.59) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL16790448 | 0.85 | KMT2A (0.63) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL29617446 | 0.85 | KMT2A (0.63) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL20464122 | 0.85 | KMT2A (0.63) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL20710654 | 0.85 | KMT2A (0.57) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL15147193 | 0.85 | KMT2A (0.57) | KMT2AEPHX2FABP7FABP5CASP3 | |
| SCHEMBL16790447 | 0.84 | KMT2A (0.62) | KMT2AEPHX2FABP7FABP5CASP3 | |
| Hydrochloric Acid SCHEMBL29617452 | 0.84 | KMT2A (0.62) | KMT2AEPHX2FABP7FABP5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982017-B2 | Synthetic apelin mimetics for the treatment of heart failure | NOVARTIS AG (CH) | 2018-05-29 | — | — | US | disclosed |