Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.81 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | BRAF | P15056 | 1/20 | 0.81 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.81 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15424103 | 1.00 | MAP2K1 (0.81) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL24223772 | 1.00 | MAP2K1 (0.81) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL25736933 | 0.92 | MAP2K1 (0.81) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL6292218 | 0.92 | MAPK1 (0.80) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4855302 | 0.91 | MAP2K1 (0.80) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL6291586 | 0.90 | MAPK1 (0.80) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL18457665 | 0.90 | MAP2K1 (0.78) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4857208 | 0.90 | MAP2K1 (0.78) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4857205 | 0.90 | MAP2K1 (0.78) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL12582182 | 0.90 | MAP2K1 (0.78) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982237-B2 | Compositions and methods for reprograming non-pluripotent cells into pluripotent stem cells | HONG GUAN, LTD. (CN) | 2018-05-29 | — | — | US | disclosed |