Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194183 | 0.75 | AAK1 (0.52) | — | |
| SCHEMBL20194167 | 0.72 | F10 (0.37) | — | |
| SCHEMBL20194187 | 0.71 | CCR3 (0.34) | EGFRBRAF | |
| SCHEMBL20194243 | 0.70 | F10 (0.42) | EGFRBRAF | |
| SCHEMBL20194172 | 0.70 | AAK1 (0.30) | — | |
| SCHEMBL20194228 | 0.70 | F10 (0.34) | EGFRBRAF | |
| SCHEMBL20194205 | 0.69 | — | — | |
| SCHEMBL20194180 | 0.69 | F10 (0.35) | EGFRBRAF | |
| SCHEMBL20194195 | 0.68 | F10 (0.36) | — | |
| SCHEMBL20194193 | 0.68 | F10 (0.36) | EGFRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054955-B1 | PYRROLOTRIAZINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-30 | — | — | EP | disclosed |