Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099056 | 0.95 | KDM4E (0.46) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL21099079 | 0.94 | HSD17B10 (0.48) | KDM4EHSD17B10MAPK1TSHRDHODH | |
| SCHEMBL21099059 | 0.94 | SMN1; SMN2 (0.46) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL17829291 | 0.92 | KDM4E (0.48) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL19039896 | 0.92 | SMN1; SMN2 (0.50) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL20195347 | 0.91 | KDM4E (0.44) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL21098948 | 0.90 | TSHR (0.46) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL18675717 | 0.90 | KDM4E (0.47) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL17343268 | 0.90 | KDM4E (0.51) | KDM4ETDP1HSD17B10MAPK1TSHR | |
| SCHEMBL17598615 | 0.90 | KDM4E (0.50) | KDM4ETDP1HSD17B10MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327008-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME | LG Chem, Ltd. (KR) | 2018-05-30 | — | — | EP | disclosed |