Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195763 | 0.95 | MAPT (0.44) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL816053 | 0.93 | MAPT (0.47) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL815927 | 0.90 | MAPT (0.45) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL20195762 | 0.90 | NPC1 (0.36) | MAPTKMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL815896 | 0.88 | MAPT (0.49) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL24086194 | 0.87 | MAPT (0.52) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL815808 | 0.87 | MAPT (0.46) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL19982370 | 0.85 | KMT2A (0.52) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL16425816 | 0.84 | KMT2A (0.53) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL19982368 | 0.84 | KMT2A (0.53) | MAPTKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261201-B1 | TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2018-05-30 | — | — | EP | disclosed |