Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15816925 | 0.87 | GRIN2B (0.39) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL12424303 | 0.86 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL10202327 | 0.86 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL8950858 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL15425362 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL705582 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL30838104 | 0.83 | GRIN2B (0.43) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL6922182 | 0.83 | GRIN2B (0.43) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL27092782 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL17400611 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |