Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 17/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197299 | 0.89 | SREBF2 (0.61) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197300 | 0.85 | SREBF2 (0.67) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL16535955 | 0.83 | SREBF2 (0.60) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197352 | 0.80 | SREBF2 (0.59) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197269 | 0.77 | SREBF2 (0.56) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197323 | 0.77 | SREBF2 (0.46) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4285116 | 0.77 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197270 | 0.77 | SREBF2 (0.53) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL20197221 | 0.77 | SREBF2 (0.55) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4292296 | 0.75 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |