Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989579 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL19479655 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL6822201 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL19479652 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL7261299 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL7739055 | 1.00 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL13207930 | 0.96 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL1117739 | 0.96 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL857551 | 0.96 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 | |
| SCHEMBL9452147 | 0.96 | PDPK1 (0.59) | PDPK1MTORBCHETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847154-B1 | RADIOTRACER, IN PARTICULAR FOR CANCER | UNIV DE LORRAINE (FR) | 2018-05-30 | — | — | EP | disclosed |