Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818662 | 0.81 | BCHE (0.55) | PDPK1MTORBCHEACHEPSEN1 | |
| SCHEMBL2887472 | 0.81 | BCHE (0.55) | PDPK1MTORBCHEACHEPSEN1 | |
| SCHEMBL7739055 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL13207930 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL857551 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL6822201 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL989579 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL21510532 | 0.74 | PDPK1 (0.55) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL21510398 | 0.74 | PDPK1 (0.55) | PDPK1MTORBCHEACHETSHR | |
| SCHEMBL7261299 | 0.74 | PDPK1 (0.59) | PDPK1MTORBCHEACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847154-B1 | RADIOTRACER, IN PARTICULAR FOR CANCER | UNIV DE LORRAINE (FR) | 2018-05-30 | — | — | EP | disclosed |