Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 16/20 | 0.41 |
| ▸ | SREBF1 | P36956 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535031 | 0.89 | SREBF2 (0.45) | SREBF2SREBF1MAPTATMKDM4E | |
| Hydrochloric Acid SCHEMBL16535162 | 0.88 | SREBF2 (0.44) | SREBF2SREBF1MAPTATMKDM4E | |
| Bromide SCHEMBL16535897 | 0.88 | SREBF2 (0.44) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535161 | 0.84 | SREBF2 (0.41) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535239 | 0.84 | SREBF2 (0.44) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535609 | 0.83 | SREBF2 (0.43) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535946 | 0.83 | SREBF2 (0.46) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535838 | 0.83 | SREBF2 (0.59) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535699 | 0.82 | SREBF2 (0.44) | SREBF2SREBF1MAPTATMKDM4E | |
| SCHEMBL16535861 | 0.81 | SREBF2 (0.48) | SREBF2SREBF1MAPTATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |