Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456323 | 1.00 | PDPK1 (0.50) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL20197127 | 1.00 | PDPK1 (0.50) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL9456326 | 1.00 | PDPK1 (0.50) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL20197126 | 1.00 | PDPK1 (0.50) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL13996383 | 1.00 | PDPK1 (0.50) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL9293835 | 0.92 | BCHE (0.52) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL9456318 | 0.92 | BCHE (0.52) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL9456071 | 0.92 | BCHE (0.52) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL6372903 | 0.92 | BCHE (0.52) | PDPK1MTORBCHEALOX15CYP3A4 | |
| SCHEMBL9439413 | 0.92 | BCHE (0.52) | PDPK1MTORBCHEALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847154-B1 | RADIOTRACER, IN PARTICULAR FOR CANCER | UNIV DE LORRAINE (FR) | 2018-05-30 | — | — | EP | disclosed |