Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184063 | 0.86 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20184007 | 0.86 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC4HDAC2 | |
| SCHEMBL20184026 | 0.84 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20183984 | 0.81 | HDAC6 (0.52) | HDAC6HDAC1HDAC8 | |
| SCHEMBL20184091 | 0.80 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20184000 | 0.80 | HDAC6 (0.51) | HDAC6HDAC1HDAC8 | |
| SCHEMBL21179859 | 0.79 | HDAC6 (0.51) | HDAC6HDAC1HDAC8HDAC4HDAC2 | |
| SCHEMBL20184038 | 0.79 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20184036 | 0.79 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20184023 | 0.79 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327019-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-05-30 | — | — | EP | disclosed |