Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.57 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.57 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700680 | 0.87 | SRPK1 (0.74) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL3485720 | 0.87 | SRPK1 (0.74) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL31187476 | 0.87 | SRPK1 (0.74) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL12765717 | 0.85 | SRPK1 (0.78) | NPSR1TSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL3485129 | 0.85 | SRPK1 (0.78) | NPSR1TSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL20198469 | 0.84 | KMT2A (0.72) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL16697303 | 0.81 | MAPT (0.64) | NPSR1TDP1TSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL2023240 | 0.80 | POLB (0.76) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL23196345 | 0.78 | MAPT (0.52) | NPSR1TDP1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL29937951 | 0.78 | HRH3 (0.61) | NPSR1TDP1SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712242-B1 | METHOD OF REGULATING PHOSPHORYLATION OF SR PROTEIN AND ANTIVIRAL AGENTS COMPRISING SR PROTEIN ACTIVITY REGULATOR AS THE ACTIVE INGREDIENT | HAGIWARA MASATOSHI (JP) | 2018-05-30 | — | — | EP | disclosed |