Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.77 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.77 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.77 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 4/20 | 0.49 |
| ▸ | LCK | P06239 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016421 | 0.88 | KDR (0.60) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL3485927 | 0.87 | SRPK1 (1.00) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL1110544 | 0.87 | SRPK1 (1.00) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL1110476 | 0.87 | SRPK1 (1.00) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL1110612 | 0.86 | SRPK1 (0.77) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL3485920 | 0.86 | SRPK1 (0.98) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL23196029 | 0.84 | CDK4 (0.74) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL1110642 | 0.81 | SRPK1 (0.80) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL8274190 | 0.76 | MAPT (0.70) | KDRSRPK1SRPK2SRPK3MAPT | |
| SCHEMBL13540499 | 0.76 | SRPK1 (0.79) | KDRSRPK1SRPK2SRPK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712242-B1 | METHOD OF REGULATING PHOSPHORYLATION OF SR PROTEIN AND ANTIVIRAL AGENTS COMPRISING SR PROTEIN ACTIVITY REGULATOR AS THE ACTIVE INGREDIENT | HAGIWARA MASATOSHI (JP) | 2018-05-30 | — | — | EP | disclosed |