Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 20/20 | 0.88 |
| ▸ | MAPT | P10636 | 11/20 | 0.88 |
| ▸ | PIM1 | P11309 | 1/20 | 0.88 |
| ▸ | CDK2 | P24941 | 1/20 | 0.88 |
| ▸ | GSK3B | P49841 | 1/20 | 0.88 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.88 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.88 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20199411 | 0.94 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL30049927 | 0.94 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL30051416 | 0.94 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL20199427 | 0.92 | GSK3A (0.85) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL21331455 | 0.91 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL20199389 | 0.86 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL30051794 | 0.86 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL21331456 | 0.86 | GSK3A (0.78) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL21331459 | 0.85 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B | |
| SCHEMBL30050288 | 0.85 | GSK3A (1.00) | GSK3AMAPTPIM1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098411-A1 | GSK-3 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-31 | — | — | WO | disclosed |