Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688780 | 0.88 | FFAR1 (0.60) | FFAR1CTSLCTSBCTSSKAT6A | |
| SCHEMBL1515758 | 0.82 | SRD5A2 (0.61) | SRD5A2FAAHMAPTL3MBTL1 | |
| SCHEMBL4768334 | 0.80 | KDM4E (0.53) | FFAR1CTSLCTSBCTSSKAT6A | |
| SCHEMBL7408937 | 0.80 | FFAR1 (0.49) | FFAR1CTSLCTSBCTSSKAT6A | |
| SCHEMBL29800516 | 0.79 | KDM4E (0.69) | FFAR1KAT6ACNR1KDM4EKDM6B | |
| SCHEMBL207017 | 0.79 | KDM4E (0.69) | FFAR1KAT6ACNR1KDM4EKDM6B | |
| SCHEMBL11633589 | 0.79 | MAPT (0.60) | SRD5A2KDM4EMAPTL3MBTL1RAB9A | |
| SCHEMBL22501619 | 0.78 | FFAR1 (0.53) | FFAR1CTSLCTSBCTSSKAT6A | |
| SCHEMBL7463211 | 0.78 | FFAR1 (0.50) | FFAR1CTSLCTSBCTSSKAT6A | |
| SCHEMBL20200083 | 0.78 | FFAR1 (0.58) | FFAR1CTSLCTSBCTSSHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148410-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | DANA-FARBER CANCER INSTITUTE, INC. | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148410-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | GLI1, SHH, HRAS | FFAR1 1847/4885CTSL 3488/4885CTSB 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.