Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732771 | 0.97 | SOS1 (0.50) | SOS1SOS2 | |
| SCHEMBL14962058 | 0.97 | SOS1 (0.50) | SOS1SOS2 | |
| SCHEMBL19199755 | 0.97 | SOS1 (0.50) | SOS1SOS2 | |
| SCHEMBL19199026 | 0.94 | SOS1 (0.48) | SOS1SOS2 | |
| SCHEMBL14962059 | 0.94 | SOS1 (0.52) | SOS1SOS2 | |
| SCHEMBL14962052 | 0.92 | SOS1 (0.50) | SOS1SOS2 | |
| SCHEMBL9965969 | 0.92 | — | — | |
| SCHEMBL14962054 | 0.88 | — | — | |
| SCHEMBL14962053 | 0.88 | SOS1 (0.52) | SOS1SOS2 | |
| SCHEMBL24081996 | 0.86 | SOS1 (0.50) | SOS1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148418-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148418-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | C1R, C9, C1S | SOS1 3861/4885SOS2 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.