Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691473 | 0.60 | — | — | |
| SCHEMBL10152389 | 0.58 | KDM4E (0.35) | LOXKDM4EGAATHRBRECQL | |
| SCHEMBL15593372 | 0.54 | — | — | |
| SCHEMBL10152392 | 0.54 | KDM4E (0.39) | LOXKDM4EGAATHRBRECQL | |
| SCHEMBL27656512 | 0.52 | — | — | |
| SCHEMBL22265028 | 0.51 | — | — | |
| SCHEMBL10819439 | 0.51 | — | — | |
| SCHEMBL21937057 | 0.50 | — | — | |
| SCHEMBL20087083 | 0.50 | KDM4E (0.36) | KDM4EGAATHRBRECQLL3MBTL1 | |
| SCHEMBL12091405 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370407-B2 | Affinity-assisted protein modification and recycling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180148472-A1 | AFFINITY-ASSISTED PROTEIN MODIFICATION AND RECYCLING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370407-B2 | Affinity-assisted protein modification and recycling | MRPL21, ACP1, MAX | LOX 821/4885KDM4E 2184/4885GAA 1151/4885 |
| US-20180148472-A1 | AFFINITY-ASSISTED PROTEIN MODIFICATION AND RECYCLING | MRPL21, ACP1, MAX | LOX 821/4885KDM4E 2184/4885GAA 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.