SCHEMBL2020173

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2048682	0.84	KCNH2 (0.58)	GRIN1GRIN2BKCNH2ADRB1ADRB2
	SCHEMBL2048683	0.84	KCNH2 (0.58)	GRIN1GRIN2BKCNH2ADRB1ADRB2
	SCHEMBL2019056	0.82	GRIN1 (0.73)	GRIN1GRIN2BLTA4HKCNH2NPC1
	SCHEMBL2019793	0.77	MAOB (0.48)	KCNH2HTR1AHTR2ADRD3DRD2
	SCHEMBL2018858	0.75	GRIN1 (0.75)	GRIN1GRIN2BKCNH2HTR1AHTR1D
	SCHEMBL2020637	0.73	GRIN1 (0.72)	GRIN1GRIN2BKCNH2LMNA
	SCHEMBL2017563	0.72	KCNH2 (0.77)	KCNH2ADRB1ADRB2ADRB3LMNA
	SCHEMBL1422302	0.72	KCNH2 (0.77)	KCNH2ADRB1ADRB2ADRB3LMNA
	SCHEMBL1422407	0.72	KCNH2 (0.77)	KCNH2ADRB1ADRB2ADRB3LMNA
	SCHEMBL2022536	0.72	MAOB (0.49)	KCNH2HTR1AHTR2ADRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.