Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952198 | 0.88 | POLB (0.41) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL26142156 | 0.79 | GAA (0.51) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL30897322 | 0.79 | GAA (0.51) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL396387 | 0.79 | CRBN (0.57) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL24113857 | 0.79 | CRBN (0.57) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL20206912 | 0.78 | CRBN (0.46) | CRBNDDB1HTTGAA | |
| Hydrochloric Acid SCHEMBL7450491 | 0.78 | GAA (0.50) | CRBNDDB1HTTGAAPOLB | |
| Hydrochloric Acid SCHEMBL7440940 | 0.77 | CRBN (0.55) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL20201818 | 0.76 | CRBN (0.43) | CRBNDDB1HTTGAAPOLB | |
| SCHEMBL19370852 | 0.76 | POLB (0.56) | CRBNDDB1HTTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |